The following positions in laboratories of EMBO community members are vacant. For information and to apply, please contact the recruiting organization or individual.
EMBO Young Investigator NetworkPostdoctoralUnited Kingdom
Type I/III interferons in mouse models of Salmonella infection
The Odendall lab studies innate immunity in host/pathogen interactions. We have two MRC-funded postdoc positions available to investigate the exciting interplay between type I and III interferons (IFNs) and Salmonella. IFNs are endogenous antimicrobials that protect tissues from infection by inducing hundreds of interferon-stimulated genes (ISGs). Our findings indicate that IFNs restrict epithelial cell infection with Salmonella, and we have identified several key ISGs responsible. However, the effects of type I and III IFNs in the context of Salmonella infection in the gut are not clear. We are looking to recruit an immunologist with experience in mouse models to complete our in vivo functional work. We have a parallel position available for a cell biologist to investigate the mechanisms underlying IFN and ISG-mediated restriction of Salmonella infection within cells. For any questions or further information, please feel free to email