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Nobel Prize awarded to EMBO Associate Member

 

 

October 4, 2016 - EMBO congratulates Yoshinori Ohsumi, Tokyo Institute for Technology, Yokohama/Japan on the award of the Nobel Prize in Physiology or Medicine 2016 for mapping genetic wiring of autophagy – the highly controlled process whereby cells break down their constituents in response to stress. He and his group identified the ATG genes that are essential for starvation-induced autophagy, linking the autophagy machinery to central signal transduction pathways and ubiquitin-like conjugation systems. In his current research, Yoshinori Ohsumi is elucidating the molecular details of membrane dynamics during autophagy. He was appointed an EMBO Associate Member in 2013.

 

Visit the Nobel Prize announcement webpage.

 

Free collection of his research papers in The EMBO Journal and EMBO reports alongside three recent reviews that illustrate how the ubiquitin system regulates autophagy and mitophagy, as well the role of the process in cancer.