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| Systems Biology in Human Health and Disease
One of the major driving forces of biological research has been to understand the factors that influence human health and cause diseases. New technological and conceptual tools to investigate, model and understand living organisms at the system level have evolved from advances in quantitative techniques, large-scale measurement methods and intimate integration between experimental and computational approaches. Systems Medicine is the name of this new discipline, emerging at the interface between Medicine and Systems Biology. A print collection of articles, recently published in Molecular Systems Biology, highlights the evolving field of Systems Medicine and illustrates the new insights gained by applying Systems Biology approaches within the context of human health and disease. Translating Systems Biology to the human 'system' will represent a formidable challenge. Revolutionary technologies, novel insights and massive digitalisation of information will call for clear thinking and innovation in the formulation of governance policies. It is the journal’s hope that providing an excerpt of some of the recent concrete contribution to the field will stimulate reflections and debates, extending beyond the Systems Biology community, so that the full potential and promises of Systems Medicine can be realised in harmony with societal standards.
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